The Manglik Lab

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  • Research
  • Members
  • Resources
  • Publications
  • Contact
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Aashish Manglik

Assistant Professor
Department of Pharmaceutical Chemistry
Department of Anesthesia

Curriculum Vitae, ​UCSF Profile
email: 
Aashish (dot) Manglik (at) ucsf (dot) edu
twitter: @AashishManglik
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Aashish was an undergraduate at Washington University in St. Louis, where he worked in the lab of Jeff McKinney on Salmonella-host interactions. He moved to California in 2008 to join the Stanford Medical Scientist Training Program. There, he worked with Brian Kobilka as a graduate student to elucidate different aspects of GPCR function, resulting in a number of important contributions to our current understanding of opioid and adrenergic receptors. After finishing his medical training in May 2016, Aashish began his independent research career as the first Stanford Distinguished Fellow at Stanford University School of Medicine within the Department of Molecular and Cellular Physiology. He subsequently began as an assistant professor at UCSF in fall of 2017.

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Jiahao Liang

Research technician
email: Jiahao (dot) Liang (at) ucsf (dot) edu
Jiahao is a Bay Area native and received his bachelor's degree from University of California, Santa Barbara in 2016. While at UCSB, Jiahao worked in the lab of Stuart Feinstein studying the structure of tau-microtubule interactions. Jiahao joined the Manglik lab in 2017 and is developing a number of key tools that will enable a wide variety of projects in the group. 

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Christian Billesbølle

Postdoctoral fellow
email: ChristianBache (dot) Billesboelle (at) ucsf (dot) edu

Christian hails from Denmark, where he received a bachelor's degree in Pharmacy and a master's degree in Human Biology at the University of Copenhagen. He conducted his graduate studies in the lab of Ulrik Gether, where he studied the mechanism of the prototypical transmembrane transporter LeuT by new spectroscopic methods. Christian spent a year in the laboratory of Jonathan Javitch as a visiting Bikuben research scholar. After a short postdoc in the lab of Hans Bräuner-Osborne's lab, Christian decided to come to the states. In the Manglik lab, he is examining the structural and biophysical basis of iron transport with support from the Alfred Benzon Foundation.

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Ishan Deshpande

Postdoctoral fellow
email: Ishan (dot) Deshpande (at) ucsf (dot) edu

Ishan received his bachelor’s and master’s degrees in Biotechnology at the University of Pune in India. He then moved to Switzerland for his graduate studies, where he worked on DNA damage signaling in the labs of Susan Gasser and Heinz Gut. With a growing interest in transmembrane signaling, Ishan decided to change fields and is currently working on Hedgehog signaling in the Manglik lab. Ishan is supported by a Swiss National Science Foundation Fellowship 

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Chase Webb

PSPG Graduate Student (joint with Shoichet Lab)
email: Chase (dot) Webb (at) ucsf (dot) edu

Chase is an Arizona transplant who received his bachelor's degree from Saint Mary's College of California in Chemistry in 2016. While at SMC, Chase worked with Dr. Ken Brown investigating the stereochemistry of magnesium mediated oxidations. After a 1 year post-baccalaureate fellowship as part of the NIH PREP program at Case Western Reserve University, Chase matriculated at UCSF in the Pharmaceutical Sciences and Pharmacogenomics Graduate Training Program. As a joint student in the Manglik and Shoichet Laboratories, Chase is interested in using computational and biophysical tools to study the pharmacological basis of GPCR mediated analgesia with support from the National Science Foundation Graduate Research Fellowship.

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Julian Harris

CCB Graduate Student
email: Julian (dot) Harris (at) ucsf (dot) edu

Julian comes to UCSF by way of Lewis & Clark College, where he received his BA in Chemistry. While at Lewis & Clark College, Julian worked in the lab of Casey Jones to design and engineer polyphenol releasing coronary arterial stents. Julian is a graduate student in the Chemistry & Chemical Biology program at UCSF. In the Manglik lab, Julian is studying GPCR-coupled activation of beta-arrestins with support from the ​National Science Foundation Graduate Research Fellowship.

Benjamin Barsi-Rhyne

Tetrad Graduate Student (joint with von Zastrow Lab)
email: ben (dot) barsirhyne (at) gmail (dot) com

Ben received his undergraduate degree from San Jose State University. While there he studied synapse formation and maintenance in the laboratory of Miri VanHoven. Currently, Ben is a graduate student in the von Zastrow and Manglik laboratories where he is developing new tools to study the role of β-arrestin in GPCR signaling and trafficking.

Manglik Lab Alumni

2016-2017
​2018
Yagmur Muftuoglu - Medscholars Student/Postdoc
Preetham Bachina - Undergraduate Summer Student
Currently: Stanford Medical Student
Currenlty: Rice Undergraduate

We are actively recruiting highly motivated graduate students and postdoctoral fellows interested in problems at the intersection of transmembrane signaling, protein biophysics, and human disease.

Interested graduate students should apply to one of the UCSF graduate programs.

Postdoctoral fellows should contact Aashish directly with a CV, research proposal, and three references.