Aashish Manglik, M.D., Ph.D.

Associate Professor
Department of Pharmaceutical Chemistry
Department of Anesthesia
​UCSF Profile
email: Aashish (dot) Manglik (at) ucsf (dot) edu
twitter: @AashishManglik
​ 
Aashish was an undergraduate at Washington University in St. Louis, where he worked in the lab of Jeff McKinney on Salmonella-host interactions. He moved to California in 2008 to join the Stanford Medical Scientist Training Program. There, he worked with Brian Kobilka as a graduate student to elucidate different aspects of GPCR function, resulting in a number of important contributions to our current understanding of opioid and adrenergic receptors. After finishing his medical training in May 2016, Aashish began his independent research career as the first Stanford Distinguished Fellow at Stanford University School of Medicine within the Department of Molecular and Cellular Physiology and started at UCSF in 2017.

Jakki Stevens

Lab Manager
email: Jacqueline (dot) Stevens (at) ucsf (dot) edu

​Jakki blurb

Christian Billesbølle, Ph.D.

Senior Scientist
email: ChristianBache (dot) Billesboelle (at) ucsf (dot) edu

Christian hails from Denmark, where he received a bachelor's degree in Pharmacy and a master's degree in Human Biology at the University of Copenhagen. He conducted his graduate studies in the lab of Ulrik Gether, where he studied the mechanism of the prototypical transmembrane transporter LeuT by new spectroscopic methods. Christian spent a year in the laboratory of Jonathan Javitch as a visiting Bikuben research scholar. After a short postdoc in the lab of Hans Bräuner-Osborne's lab, Christian decided to come to the states. In the Manglik lab, Christian has explored many different directions in transporter and GPCR biochemistry and biophysics.

Yue Wan, Ph.D.

Postdoctoral fellow
email: Yue (dot) Wan (at) ucsf (dot) edu

Yue blurb

Chase Webb

PSPG Graduate Student (joint with Shoichet Lab)
email: Chase (dot) Webb (at) ucsf (dot) edu

Chase is an Arizona transplant who received his bachelor's degree from Saint Mary's College of California in Chemistry in 2016. While at SMC, Chase worked with Dr. Ken Brown investigating the stereochemistry of magnesium mediated oxidations. After a 1 year post-baccalaureate fellowship as part of the NIH PREP program at Case Western Reserve University, Chase matriculated at UCSF in the Pharmaceutical Sciences and Pharmacogenomics Graduate Training Program. As a joint student in the Manglik and Shoichet Laboratories, Chase is interested in using computational and biophysical tools to study the pharmacological basis of GPCR mediated analgesia with support from the National Science Foundation Graduate Research Fellowship.

Matthew Howard

Tetrad Graduate Student (joint with Coyote-Maestas Lab)
email: Matthew (dot) Howard (at) ucsf (dot) edu

Matt Blurb

Luis Santiago

PSPG Graduate Student (joint with von Zastrow lab)
email: Luis (dot) Santiago (at) ucsf (dot) edu

Luis Blurb

Nick Hoppe

Biophysics Graduate Student 
email: nick (dot) hoppe (at) ucsf (dot) edu

Nick grew up in Wisconsin, and received his BS in biomedical engineering and applied math from UW-Madison. Before joining UCSF’s biophysics PhD program, Nick worked as a research technician in Srivatsan Raman’s lab designing biosensors. Nick is now studying the molecular mechanisms of GPCRs that control a range of physiological processes spanning morphogenesis, breathing, and nociception.

Simone Harrison

Biophysics Graduate Student 
email: simone (dot) harrison (at) ucsf (dot) edu

Simone received her bachelor’s degree in Molecular Biology and Biochemistry from Wesleyan University in 2018. At Wesleyan, she worked in the Olson lab to study the biophysical properties of novel pathogenic proteins from the genus Vibrio. After college, Simone worked for 2 years at Vanderbilt University in the Chazin lab as a Research Assistant, studying the structural basis of nutrient sequestration and inflammation mediated by S100 proteins, and aiding with protein production. In the Manglik lab, she is studying the molecular details of the interaction between GPCRs and GRKs, as well as the mechanism of GPCR mediated regulation of the hedgehog signaling pathway.

Linus Li

Postbac student
email: Linus (dot) Li (at) ucsf (dot) edu

Linus Blurb

Manglik Lab Alumni

2016-2017
​2018
2019
2018-2019
​2019
​​2017-2020
2021
​2021
2018-2021
​2020-2022
2017-2022
2018-2022
​2019-2022
​2022
Yagmur Muftuoglu - Postdoc
Preetham Bachina - Undergraduate Summer Student (Rice Univ.)
Simon Schneider - Master's Student (Goethe Univ.)
Anastasiia Sukalskaia - Master's Student (Univ. Copenhagen)
Zhen Tong - Undergraduate Student (Nankai Univ.)
​Jiahao Liang - Research Associate/Lab Manager
Ashley Olivares Rojas - BAYS Program Summer Student
Dora Obgonna - SRTP Summer Student
Ishan Deshpande - Postdoc
Melanie O'Rourke - Lab Manager
​Benjamin Barsi-Rhyne - Graduate Student
Julian Harris - Graduate Student
​Bryan Faust - Graduate Student
Megan Xu - Undergraduate Summer Student (Cornell Univ.)
Next: Stanford Medical Student
Next: Rice Undergraduate
Next: Master's Student
Next: Graduate Student, U Zurich
Next: Graduate Student, U Chicago
​Next: Graduate Student, Stanford
Next: High School Student, KIPP
​Next: UCSD Undergrad
​Next: Group leader, Genentech
Next: Lab Manager, Glyphic Bio
Next: Scientist, Vicinitas
​Next: Instructor, University of Delaware
Next: Deal Analyst, Andreesen Horowitz
Next: Cornell Undergraduate
We are actively recruiting students and postdoctoral fellows interested in problems at the intersection of transmembrane signaling, protein biophysics, and human disease.

Interested graduate students should apply to one of the UCSF graduate programs.

Postdoctoral fellows should contact Aashish directly with a CV, research proposal, and three references.